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Luteinizing hormone. This is the hormone that makes the egg (follicle) release from the ovary. This hormone is involved in the process of ovulation – the time in the menstrual cycle when the follicle ruptures and releases the egg from the ovary. Faiman C, Ryan RJ: Serum follicle-stimulating hormone and luteinizing hormone concentrations during menstrual cycle as determined by radioimmunoassays.